tag:blogger.com,1999:blog-5239665991629834606.post675092089098906869..comments2024-02-24T21:08:24.026-06:00Comments on Positives About Negative: New Target for TNBC Found, Say UC Berkeley ResearchersPatricia Prijatelhttp://www.blogger.com/profile/08346233311451068354noreply@blogger.comBlogger12125tag:blogger.com,1999:blog-5239665991629834606.post-11933997587876210222016-05-13T18:12:06.004-05:002016-05-13T18:12:06.004-05:00Generic indeed. Ugh.Generic indeed. Ugh.Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-13499119342011315922016-05-13T17:27:09.037-05:002016-05-13T17:27:09.037-05:00Her is the response I recieved.Its a generic lette...Her is the response I recieved.Its a generic letter sent to anyone who inquires.<br />Dear Joy, <br /><br />Thanks for your interest in our study. We discovered a new TNBC drug target called GSTP1 that regulates glucose metabolism in TNBC cells. We've been able to show that we can regress TNBC tumor growth in mice with GSTP1 inhibitors through impairing glucose metabolism in TNBC cells that feeds into lipid and nucleotide metabolism that the cell needs to make cell membranes and DNA necessary for cells to proliferate. We hope eventually to translate GSTP1 inhibitors into the clinic but this will take many more years. <br /><br />It is for people like you that our lab works hard to try to develop new treatments and hopefully cures for TNBCs.<br /><br />You can read more about our study on our lab website: www.nomuraresearchgroup.com<br />at http://nomuraresearchgroup.com/wp-content/uploads/Louie-et-al-2016-Cell-Chem-Biol.pdfJoy Svensonhttps://www.blogger.com/profile/17800297125457531333noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-89113693983346847062016-05-13T10:02:28.824-05:002016-05-13T10:02:28.824-05:00I am not a fan of taking vitamins in general, but ...I am not a fan of taking vitamins in general, but advocate natural sources for healthy nutrients when it is possible. Lots of research has shown that eating fruits and vegetables is especially important in combatting TNBC and that cruciferous vegetables can reduce the risk of TNBC. But glutathione is in cruciferous vegetables. So, does this research counters those previous studies? We don't know yet, but I suspect not. I suspect the truth will end up being far more complicated and will come down, once again, to individual reactions, to our cancers being as unique as our DNAs. So my advice is to eat your fruits and vegetables, including the cruciferous, which includes broccoli and cabbage and kale, but not take vitamin supplements because the latter are too concentrated and might not offer a natural balance. If you are worried, then cut down on the amount of cruciferous veggies, but still eat lots of other fruits and veggies. Still, you might contact the researchers and get their take. At this point, I think the takeaway is: Yay! We might be finally close to that target, the drug for TNBC that does what Herceptin does for Her2-positive. Let's wait until the actual mechanics are clearer. Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-42897846442268629322016-05-13T08:40:26.657-05:002016-05-13T08:40:26.657-05:00This comment has been removed by the author.Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-9940866040429315182016-05-13T07:50:25.318-05:002016-05-13T07:50:25.318-05:00Patricia how glutathione good after this report ? ...Patricia how glutathione good after this report ? Thanks I have some woman worried!Joy Svensonhttps://www.blogger.com/profile/17800297125457531333noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-3633051509640972622016-05-12T22:03:28.081-05:002016-05-12T22:03:28.081-05:00This comment has been removed by the author.Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-86638003925498126542016-05-12T21:35:57.551-05:002016-05-12T21:35:57.551-05:00I lost my beautiful Shani in January to this dread...I lost my beautiful Shani in January to this dreaded cancer. I am so hopeful for a targeted treatment. I only wish something would have came along several years ago. But anything that could help anyone else not suffer would be great. The immuno therapy drugs look promising as well. We will keep praying for something good to happen. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-57400129342753567102016-05-12T18:47:19.578-05:002016-05-12T18:47:19.578-05:00I was going to buy the vitamin Glutathione, does t...I was going to buy the vitamin Glutathione, does this mean I shouldn't take it????Anonymoushttps://www.blogger.com/profile/16713320043918009341noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-20364904749080557132016-05-12T17:33:14.768-05:002016-05-12T17:33:14.768-05:00I've thought for some time that we are on the ...I've thought for some time that we are on the cusp of a new treatment. So something might happen soon with other research. Lots is going on, finally, with TNBC research.Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-48551625233587279302016-05-12T17:18:51.449-05:002016-05-12T17:18:51.449-05:00I am so happy, a target...I posted it on my site f...I am so happy, a target...I posted it on my site for my girls. I also posted it on a couple more but they are just asking when are trials, I know for some they fear it wont be in time for them. Just breaks my heart....but it seems so promising!Joy Svensonhttps://www.blogger.com/profile/17800297125457531333noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-29482473983928450522016-05-12T17:13:43.149-05:002016-05-12T17:13:43.149-05:00I just got the release, so maybe it will make it. ...I just got the release, so maybe it will make it. Still, TNBC is not exactly a media darling. Also, the research is in mice, which means it will take a few more steps before we know if it will work in humans.Patricia Prijatelhttps://www.blogger.com/profile/08346233311451068354noreply@blogger.comtag:blogger.com,1999:blog-5239665991629834606.post-6079550319202654052016-05-12T17:10:29.219-05:002016-05-12T17:10:29.219-05:00This is huge, why isnt it on the news... this is g...This is huge, why isnt it on the news... this is great!Joy Svensonhttps://www.blogger.com/profile/17800297125457531333noreply@blogger.com