High BMI Linked to TNBC

Significant increases in body mass index are associated with an increased risk of triple-negative breast cancer, according to research published in the journal Cancer, produced by the American Cancer Society.  In the study, women who went up ten points or more—from, for example, a BMI of 22 to one of 32—between the ages of 18 and 44 doubled their risk of TNBC.   There was no increased risk of estrogen-positive breast cancer.

The sampling included women ages 20 to 44 years who were diagnosed from 2004 to 2010 in the Seattle-Puget Sound metropolitan area:
• 779 with estrogen receptor-positive breast cancer
•182 triple-negative breast cancer
• 60 with ER-negative/HER2-overexpressing, invasive breast cancer
• 939 cancer-free controls.  

This supports a fairly large body of research that has associated weight gain with TNBC risk.

Read more about BMI and TNBC, plus a roadmap for a healthy lifestyle, in my book, Surviving Triple-Negative Breast Cancer.

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