[Information
below is from Boston
University and has been edited to eliminate misleading comments, such as
that triple-negative breast cancer is automatically aggressive.]
African-American
women who have had children and never breastfed appear to have an increased
risk of developing estrogen receptor-negative breast cancer, including
triple-negative breast cancer, according to a study published in the Journal
of the National Cancer Institute.
This
is consistent with previous
research that showed that breastfeeding reduced
TNBC risk in all women.
Researchers
combined data on breast cancer cases and controls from four large studies,
including the Boston University Black Women's Health Study. The combined
analyses included 3,698 African American women with breast cancer, including
1,252 with the estrogen receptor-negative subtype.
They
found that women who had four or more births and had never breastfed any of
their babies had a 68 percent higher chance of developing this type of cancer
compared with women who had only one birth and had breastfed that baby.
African-American
women are more likely die of breast cancer than white women, and are more
likely to be diagnosed with triple-negative.
Although
previous studies have shown that overall risk of breast cancer may be elevated
during the first 5 or 10 years after giving birth with a subsequent reduction
in risk, this study suggests that the adverse impact on estrogen receptor
negative breast cancer persists over time. The biologic mechanisms behind the
association, however, are unclear. One hypothesis is that the immune system/inflammatory
processes that occur after birth may play a role.
Whatever the cause,
breastfeeding looks like one way to reduce risk—not to mention that it is just
good for both mom and baby.
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